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Online Resources for Science Educators
The Stem Cell Game
Authors:
Alexandra Manaia and Julia Willingale-Theune

Description:
Cells are the basic building blocks of the human body. They make up the skin, muscles, bones and all of the internal organs. They also hold many of the keys to how our bodies function.

Like the body itself, cells have a finite life span; they eventually die. Most of the body's cells divide and duplicate throughout life, but some cells either don't replenish themselves or do so in such small numbers that they cannot replace themselves fast enough to combat disease.

Scientists first discovered stem cells in mice in the 1970s. They soon began to recognize the amazing versatility of these primitive cells, which exist for only a short time before differentiating into the many cell types of the body. However, it wasn't until 1998 that the first human stem cells were isolated by James Thomson at the University of Wisconsin and John Gearhart at The Johns Hopkins University.

Stem cells have the remarkable potential to develop into many different cell types in the body. Serving as a sort of repair system for the body, they can theoretically divide without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential to either remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Target Audience:
Age 16-18 years

Objective:
'The Stem Cell Game' presents a basic A to Z of stem cells, reviewing where they are found in the body, the different types, how they are cultured and examples of stem cell therapy that rely on replacing diseased or dysfunctional cells with healthy, functioning ones. It is designed as a non-formal teaching aid to reinforce the syllabus.

GCSE Syllabus:
Advanced Subsidiary GCE and Advance GCE specifications for Human Biology
This activity can be used to review and reinforce concepts taught in the module:
The Developing Cell
'Using stem cell technology'

Candidates should be able to:
a. define the term stem cell
b. explain the term differentiation
c. define how stem cells are cultured and discuss the potential benefits of stem cell technology.

Materials:
The cardsfront.pdfs are the 'Questions' and the back .pdf are the corresponding 'Answers'. After printing them out you will have to stick the questions and answers together to produce the question cards-the questions on the front and the answers on the reverse side! The same procedure needs to be done for the rescue cards.

Rules
Rules [PDF]

Playing Cards
Cards front 1 [pdf]
Cards front 2 [pdf]
Cards front 3 [pdf]
Cards back [pdf]
Rescue questions front [pdf]
Rescue questions back [pdf]

Board
Stem Cell Game [PDF]
Back
European Learning Laboratory for the Life Sciences (ELLS)
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